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Foot-and-mouth disease is an acute, feverish, highly contagious infectious disease that coexists in major livestock such as swine, livestock and sheep, as well as domesticated and wild artiodactyls. The number of animals that can be easily attacked by this disease reaches over 70. Clinical symptoms consist of vesiculobullous rashes occurring on mouth mucosa, hoof and breast skin. Featured with multiple transmission routes and a high transmission rate, it used to break out and become prevalent worldwide repeatedly, which gives rise to great political and economic losses.
With progress in animal husbandry, rearing cattle has become a critical means of livelihood. As the most serious disease that endangers animal production, livestock diseases not only lead to death of livestock in batches, but also bring about huge economic losses. In addition, some zoonosis may also affect international trade reputation and threatens physical health. Especially in ever-growing intensive livestock farms of mass production, epidemic diseases have been deemed as important factors that hinder production development and impair economic benefits.